CRS-7

A single strut held a pressurized helium bottle inside the second stage's liquid oxygen tank. On 28 June 2015, 139 seconds after CRS-7 lifted from Cape Canaveral, that strut gave way — rated for 10,000 pounds of load, it failed at roughly 2,000. The freed bottle ruptured the oxygen tank, and the Falcon 9 broke apart over the Atlantic. It was SpaceX's first in-flight loss of a Falcon 9.

The Dragon capsule separated from the disintegrating vehicle and continued transmitting, but its software carried no procedure for deploying parachutes during a launch abort, and it was lost on impact with the ocean. The International Docking Adapter — IDA-1, destined to upgrade a berthing port on the station — went down with it. Falcon 9 did not fly again for six months.