Pléiades Neo 5 & 6

Pléiades Neo 5 and 6 were the final two satellites needed to complete Airbus Defence and Space's four-satellite Pléiades Neo constellation. Both were lost when the Zefiro 40 second stage deviated from its intended trajectory following a pressure loss, causing reentry about 917 km (570 mi) north of the launch site over the Atlantic.

VV22 was Vega-C's first commercial mission, following the vehicle's inaugural test flight in July 2022.